Abstract
Obesity and severe obesity are increasing serious health problems with an epidemic percentage in most countries. In Sleeve gastrectomy, a part of the stomach structure is removed, limiting its capacity by about two to three. A total of thirty blood samples were collected from patients with obesity and the result was compared with healthy person throughout the time from November 2019 to September 2020. Before sleeve gastrectomy and after more than 6 months of sleeve surgery, the sample was collected from the Medical City/Baghdad Teaching Hospital, the withdrawal was again taken at home to have pre and post sleeve gastrectomy, Patient age ranged between [20-46] years for obese patients and healthy control. Then the serum samples were obtained from patients and control group to screen for C-reactive protein by agglutination method. The result of the present study found that the positivity of CRP in pre-operation is higher than that of post-operative with high significance [P<0.005].
Highlights
Obesity is associated with chronic low-grade inflammation that is described by raising levels of systemic inflammatory markers such as Creactive protein (CRP), interleukin-6(IL-6), interleukin-18(IL-18) and tumour necrosis factor-α (TNF-α)
Obesity is associated with chronic low-grade inflammatory activity, which is charsacterised by elevated inflammatory marker level such as CRP [1]
Plasma concentrations of IL-6, IL-18 and TNF-α stayed constant after gastric bypass [2]
Summary
Obesity is associated with chronic low-grade inflammation that is described by raising levels of systemic inflammatory markers such as Creactive protein (CRP), interleukin-6(IL-6), interleukin-18(IL-18) and tumour necrosis factor-α (TNF-α). Obesity is associated with chronic low-grade inflammatory activity, which is charsacterised by elevated inflammatory marker level such as CRP [1]. Plasma concentrations of IL-6, IL-18 and TNF-α stayed constant after gastric bypass [2]. The decreased BMI ratio is significantly correlated with changes in the plasma C-reactive protein (hs-CRP) [4]. Lipid and cytokine mediators are the primary inflammatory response modulators in arthritis, both of which are known to be involved in the development of joint inflammation, the development of arthritic pannus plays an especially critical role and contributes significantly to the production of pro-inflammatory cytokines and potent chemokines. Lipid and cytokine mediators are the primary inflammatory response modulators in arthritis, both of which are known to be involved in the development of joint inflammation, the development of arthritic pannus plays an especially critical role and contributes significantly to the production of pro-inflammatory cytokines and potent chemokines. such as IL-8, responsible for joint inflammation [5]
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