Abstract

The coagulopathy caused by SARS-CoV-2 seen in patients hospitalised with COVID-19, especially those with severe or critical illness, is by now well established. Early reports in relatively small studies showing multifold elevated rates of both venous and arterial thromboembolism have given way to more sober estimates from much larger populational studies and systematic reviews or meta-analyses. Overall rates of venous thromboembolism, including in-situ pulmonary thrombosis, are approximately three-times higher than historical matched controls of hospitalised populations, whereas rates of arterial thromboembolism, including acute coronary syndromes and stroke, although still elevated, are lower than previously described.

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