Studying the Alkaloids Content in Delphinium oreophilum Huth

Abstract

Research relevance: plant alkaloids are important in pharmacology based on their high physiological activity, as well as wide range of practical valuable medicinal properties. Most of plants necessary for conservation, cultivation and rational use of each type of plant resources in traditional and medical practice remains an urgent task. Kyrgyzstan is a favorable region for growth of medicinal herbs that is why flora research and study is of great importance. Research objectives: search of the biologically active content of methyllicaconitine alkaloids in roots and aerial parts of the Delphinium oreophilum plant growing in the territory of the Kyrgyz Republic. Research methods: diterpenoid alkaloids methyl lycaconitine, anthranoillicoctonine, lycoctonine, eldelin, eldelidine were obtained by separating the sum of alkaloids. Resulting compounds were analyzed by IR, NMR, Mass spectroscopy. A mixed melt test of the isolated perchlorate with a true sample of methyl lycaconitine perchlorate confirmed compounds identity. Research results: the sum of alkaloids obtained from the roots and aerial parts of Delphinium oreophilum plants collected in the southern and northern slopes of the Kichi Alai ridge. Conclusions: the content of total alkaloids in the roots and aerial parts of the plant growing in the southern slopes was 1.8% and 1% of the weight of the dry plant. The samples collected in the northern slopes contained 0.8% and 0.7% of the total alkaloids, respectively.