Abstract
Mutans streptococci (MS) have been implicated as primary causative agents of dental caries in humans and experimental animals.14,15 Among these organisms, Streptococcus mutans (serotypes c, e, and f) and Streptococcus sobrinus (serotypes d and g) are frequently isolated from human dental plaque.26 Dental plaque is a complex but typical bacterial biofilm, which contains MS and other oral bacteria and their products. Dental plaque is formed in two different stages; the initial and reversible attachment of oral bacteria (mainly streptococci) to the tooth surface, and subsequent sucrose-dependent firm and irreversible adhesion of MS and other organisms.
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