Abstract
Study to assess the prevalence of antiphospholipid syndrome (APS) among women with adverse pregnancy outcome in a tertiary care centre
Highlights
Antiphospholipid syndrome is an autoimmune condition characterized by vascular thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies
Pregnancy wastage occurred in 22.7 % of APLA + ve cases following appearance of foetal cardiac activity
In the present study out of 216 cases of patients with adverse pregnancy outcome, 27 cases were found to be APLA positive giving a prevalence of 12.5%
Summary
Antiphospholipid syndrome is an autoimmune condition characterized by vascular thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies. Methodology: Patients registered in O &G Department SAT Hospital, Medical College, Trivandrum, Kerala with adverse pregnancy outcomes meeting the inclusion and exclusion criteria were recruited for the study. They were followed up in the postnatal ward after abortion and preterm delivery as per protocol for bad obstetrics outcome evaluation. They were offered lab test in standard labs for APL Syndrome especially LAC and anti-cardiolipin antibodies IgM & IgG. Vascular thrombosis-One or more clinical episodes of arterial, venous or small vessel thrombosis in any tissue or organ
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