Abstract
Aim: to analyze the drug sensitivity profile of the patients suffering from sore throat.
 Materials and Methods: The present prospective observational study was conducted in the Department of ENT, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar. Among 200 patients of either gender and of any age group attended the OPD of the ENT presented with the complaint of sore throat, throat pain, throat irritation, throat itching and foreign body sensation were recruited. A thorough ENT examination is done including ear examination, throat examination, and nasal examination. Throat swab samples collected through a sterile culture sensitivity tube and sent to microbiological lab and culture sensitivity reports collected from the patients during follow up visits.
 Results: majority of the patients were male 58.5% and rest 41.5% were female. Gram negative organisms are detected in (70.5%), Gram positive organisms detected (21.0%), and no organism detected (8.5%) of the swab samples.
 Conclusion: gram positive organisms were resistant to benzyl penicillin or ampicillin, clindamycin, ciprofloxacin or levofloxacin and sensitive to tetracycline, gentamicin, linezolid. Gram negative organisms were resistant to ampicillin, amoxyclav and sensitive to pipracillin or tazobactum, cefoperazone, amikacin, gentamicin, imipenem, cefepime, ciprofloxacin.
 Keywords: couture, throat swab, gram positive, gram negative, throat infection
Highlights
Antibiotic resistance is emerging as an important public health issue,[1,2] and overuse of antibiotics by physicians has been implicated as contributing to the problem.[3,4]
More than one-third of all antibiotics prescribed for respiratory infections are because of sore throat,[1] and one in two patients presenting to their general practitioner (GP) with these symptoms receive antibiotics.[5,6]
Sore throat is a common complaint in upper respiratory tract infections and may indicate infection with group A Streptococcus (GAS).[13]
Summary
Antibiotic resistance is emerging as an important public health issue,[1,2] and overuse of antibiotics by physicians has been implicated as contributing to the problem.[3,4] More than one-third of all antibiotics prescribed for respiratory infections are because of sore throat,[1] and one in two patients presenting to their general practitioner (GP) with these symptoms receive antibiotics.[5,6]. Meta-analysis of randomized controlled trials of antibiotics for sore throat have shown that they only provide a small reduction in symptom severity and duration (1 day).[7] Survey studies have shown that 1 in 5 patients taking broad-spectrum antibiotics and 1 in 12 taking narrowspectrum antibiotics suffer side effects such as a rash or gastrointestinal upset.[8,9,10,11,12]. Reports from various countries estimate that an antibiotic is prescribed in 30% to 75% of visits.[19,20,21,22] This suggests that antibiotics are prescribed more often than necessary
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