Study the Protective Role of Arabic Gum Extract on Some Physiological and Histological Criteria for Liver of Male Rabbit Treated with Atrazine

Abstract

The study involved fifteen health adult male rabbit white (Lepus arcticus), weight ranged (1480-1550) kg. and age between 6 to 8 month, divided to three groups the first group treated 10 ml of atrazine orally for five rabbits daily for two weeks and second group is treated with aqueous extract of Arabic gum (AG) (Acacia Senegal )30% and atrazine 10 ml between one day and another for two weeks and third group was the control group given 10 a normal saline. In the search the levels of hepatic enzyme were presented (AST) Aspartate transaminase, (ALT) Alanine transaminase and (ALP) Alkaline phosphate, also the rate of diameters of liver sinuses, the diameters of central veins and hepatocellular diameter, and found through this study: ? The presence of a significant increase (P?0.05) in the levels of hepatic enzyme (AST), (ALT) and (ALP) and rate of diameters each of liver sinuses, central veins, and hepatic cells in atrazine group compared with the control group. ? The presence of significant decrease (P?0.05) in levels of hepatic enzyme (AST) and (ALT) in the group treated with aqueous extract of AG in 30% concentration and 10 ml of atrazine compared with control group, and did not occur significant differences (P?0.05) in the level of (ALP) and in rate of diameters each of liver sinuses ,central veins , and hepatic cells in aqueous extract of Acacia Senegal and atrazine group compared with the control group