STUDY THE IN HOSPITAL MORTALITY AND MORBIDITY IN PATIENTS OF ACUTE MYOCARDIAL INFARCTION WITH RESPECT TO SERUM MAGNESIUM LEVELS

Abstract

Magnesium improves myocardial metabolism, reduces platelet aggregation, decreases systemic vascular resistance, dilates coronary arteries, guards against catecholamine induced myocardial necrosis, and stabilizes cell membranes. Ventricular tachyarrhythmia, sudden cardiac death and re-infarction are frequently results of hypomagnesaemia in the early post-acute myocardial infarction (AMI) period. In this prospective observational study, all patients presenting in the emergency with Acute onset anginal chest pain and associated symptoms were screened for AMI by obtaining an Electrocardiogram and Biochemical Markers. For those diagnosed to have ST elevation myocardial Infarction were subjected to detailed clinical history and examination. Serum Magnesium levels and Electrolyte would be obtained within 6 hours of the admission. Patients were treated as per the standard line of management on the advice of the treating physician/ cardiologist. In the present study there is Summary: signicant association seen between serum magnesium level and arrhythmia, morbidity of the study subjects, need of ventilator support, mortality, history of alcoholics, serum potassium level and serum troponin. I level in the study subjects. On the basis of present study, it is concluded that Magnesium plays a cardinal role in management and prevention of complications related to cardio-vascular event and its estimation in acute myocardial infarction serves as a tool for assessment of severity of the disease and envisage possible adverse outcomes including prevention of morbidities and mortality associated with hypomagnesemia in acute myocardial infarction patients