Abstract
Infertility is the inability of couples to achieve pregnancy after one year of regular unprotected coitus. Infertility is the problem of 15% of young couples in different countries and male factor infertility accounts for 50% of cases. Melatonin or 5-methoxy-N-acetyltryptamine was discovered by Aaron Lerner in 1958 while studying bovine pineal glands. Significant advancements have been made in the research on melatonin, which has revealed its vital roles in regulating sleep-wake cycle rhythms, decelerating the aging process, and functioning as an antioxidant or anti-inflammatory agent. Additionally, melatonin, a critical component in reproductive functions, has the ability to eliminate free radicals such as (ROS).
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