Abstract
Background: Meconium is the rst faeces of a newborn. The incidence of meconium stained liquor is 10- 15% of deliveries; out of which 5% develop meconium syndrome. It is regarded as a sign of fetal compromise. Objectives: To study the frequency and risk factors of Meconium Aspiration Syndrome in newborn Method: It is a hospital based, prospective, cohort study comprising of neonates. Setting Neonatal intensive care unit (NICU) of the Department of Paediatrics and Post Natal ward. Sample size - 4pq/e2 = 81. Inclusion criteria: In born neonates born to mothers with meconium stained amniotic uid. Out born neonates who present in the NICU within one hour of birth with history of MSAF along with staining of skin, nails and umbilical cord. Results: There were 847 deliveries during the study period. Frequency of babies born with meconium stained amniotic uid (MSAF) was 9.6%. The frequency of meconium aspiration syndrome (MAS) out of total MSAF deliveries was (7.4%). Conclusion: Meconium aspiration syndrome is one of the most common problems in the newborn and contributes signicantly to the neonatal morbidity and mortality.MAS was signicantly associated with maternal risk factors like preeclampsia, oligohydroamnios and birth factors like prolonged duration of labour, low Apgar score of 1 and 5 min
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