Abstract

Background: Meconium is the rst faeces of a newborn. The incidence of meconium stained liquor is 10- 15% of deliveries; out of which 5% develop meconium syndrome. It is regarded as a sign of fetal compromise. Objectives: To study the frequency and risk factors of Meconium Aspiration Syndrome in newborn Method: It is a hospital based, prospective, cohort study comprising of neonates. Setting Neonatal intensive care unit (NICU) of the Department of Paediatrics and Post Natal ward. Sample size - 4pq/e2 = 81. Inclusion criteria: In born neonates born to mothers with meconium stained amniotic uid. Out born neonates who present in the NICU within one hour of birth with history of MSAF along with staining of skin, nails and umbilical cord. Results: There were 847 deliveries during the study period. Frequency of babies born with meconium stained amniotic uid (MSAF) was 9.6%. The frequency of meconium aspiration syndrome (MAS) out of total MSAF deliveries was (7.4%). Conclusion: Meconium aspiration syndrome is one of the most common problems in the newborn and contributes signicantly to the neonatal morbidity and mortality.MAS was signicantly associated with maternal risk factors like preeclampsia, oligohydroamnios and birth factors like prolonged duration of labour, low Apgar score of 1 and 5 min

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