Abstract
This study aims to assess the bactericidal activity of Propolis extract against methicillin resistance Staphylococcus aureus (MRSA) in vivo. It included (11 male white New Zealand rabbits) evenly divided into two groups (6 animals in each one). Group I was fed daily with one milliliter of 20% extract Propolis for twenty days, while group II was fed without Propolis to serve as a control group. Ten days after the last dose, all animals were injected in intraperitoneal with single dose viable MRSA antigen at 0.5 x108 cfu/ml. After two days, blood samples that collected from all animals by heart puncture were cultured on blood agar media to assess bactericidal power activity of extract Propolis. The results pointed to effect of this extract on survive viable MRSA bacteria as compared with survive of same bacteria in control group animals. It was concluded Propolis had bactericidal power against pathogenic bacteria that appear resistant to antibiotics like MRSA bacteria.
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