Study protocol of the InterVitaminK trial: a Danish population-based randomised double-blinded placebo-controlled trial of the effects of vitamin K (menaquinone-7) supplementation on cardiovascular, metabolic and bone health

Freja Bach Kampmann,Marie Frimodt-Møller,Axel Diederichsen,Janne Petersen,Allan Vaag,Rikke Kart Jacobsen,Michael Huy Cuong Pham,Allan Linneberg,Camilla Friis Bryde Nielsen,Niklas Rye Jørgensen,Klaus Fuglsang Kofoed,Sanne Marie Thysen,Lars Køber,Line Lund Kårhus

doi:10.1136/bmjopen-2023-071885

Study protocol of the InterVitaminK trial: a Danish population-based randomised double-blinded placebo-controlled trial of the effects of vitamin K (menaquinone-7) supplementation on cardiovascular, metabolic and bone health

Freja Bach Kampmann, Marie Frimodt-Møller + Show 12 more

Open Access

https://doi.org/10.1136/bmjopen-2023-071885

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Journal: BMJ Open	Publication Date: May 1, 2023
Citations: 1	License type: open-access

Affiliation: Steno Diabetes Center, Copenhagen University Hospital, Frederiksberg Hospital, Center for Clinical Research and Prevention, Odense University Hospital, University of Copenhagen, Skåne University Hospital, Lund University, Rigshospitalet

#Progression Of Coronary Artery Calcification #Detectable Coronary Artery Calcification + Show 8 more

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Abstract

IntroductionVitamin K has been suggested to have protective effects against progression of vascular calcification and development of cardiovascular disease (CVD). However, few well-powered randomised controlled trials have examined whether vitamin...

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