Study pattern of antibiotic resistance on staphylococcus aureus isolated from hospitals in AL-najaf city

Abstract

Due to the improper use of antimicrobial drugs, rates of morbidity and mortality from antimicrobial resistance have been rising globally. Consequently, increasing our knowledge of and data on antimicrobial resistance in clinical settings makes it feasible to treat patients with more selective antimicrobial medications and lower the likelihood of resistance. Of the 100 isolates, 45 were female and 55 were male. Only 46 isolates have ability to growth on mannitol agar and only 21 isolates detect as S. aureus by Vitek-2, the study revealed that approximately S. aureus and S. pseudintermedius and S. sciuri with probability of 45.6 % and 34.7%, 19% respectively. For every S. aureus isolate, an antimicrobial susceptibility test against eleven antibiotics was conducted. should look into the pattern of multidrug resistance and the best course of treatment for this kind of bacteria. The susceptibility test was conducted using the antibiotic disc diffusion method, all isolate resistance to penicillin (100%), all S. aureus isolated was resistant to Tetracycline, Amikacin, Tobramycin, Gentamicin, Doxycycline, and Chloramphenicol with percentages of 95%, 88%, 75%, 64%, 75%, and 100%, respectively. The result showed the sensitive rate of S. aureus to Trimethoprim\Sulphamethoxazole and Trimethoprim and Rifampicin, Norfloxacin was 85%, 74%, 95%, 90%, it the most effective drugs used in the present study and which showed the lowest rates of resistance. The aim of this study is to study the resistance pattern of s. aureus bacteria isolated from patients suffering from skin diseases, including diabetic foot, burns, and others, collected from hospitals in the city of Najaf.