Abstract

We retrospectively reviewed and discussed hematostatic managements for tooth extraction in patients maintained on oral anticoagulant.From 2001 to 2007,109 patients maintained with oral anticoagulant treatment underwent a total of 143 occasions of tooth extraction in our department.At the time of tooth extraction, oral anticoaglant medication was maintained on 76 occasions (53%), and had been discontinued on 55 occasions (38%).Postoperative bleeding happened in 5 cases (9.1%)in patients without interruption of oral anticoagulant,and in 3 cases (3.9 %)in patients with interruption.There was no significant difference in the Prothrombin Time International Normalized Ratio (PT-INR)and in postoperative hemostatic procedures between them.The results of this study suggest that dental extraction can be performed without modification of oral anticoagulant treatment in cases where the PT-INR is less than 3.0.Strict local hemostatic procedures are necessary to prevent postoperative bleeding.Shinshu Med J 58 : 301―305, 2010 (Received for publication June 10,2010;accepted in revised form July 28,2010)

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