Study on the Supramolecular Interaction of Dopamine with Carbon Nanotubes and β-Cyclodextrin Immovilized over a Carbon Paste Electrode

Abstract

This paper showed that dopamine interacted with β-cyclodextrine, β-CD, to form an inclusion complex, which is also well known as a supramolecular complex. Once formed, such complex was applied to design an analytical method to pursue the quantitative determination of dopamine in a pharmaceutical sample, with good analytic parameters. The results are presented here of the modification carried out to the surface of a simple carbon paste electrode with multiwall carbon nanotubes, MWCNT, and with b-cyclodextrin, β-CD, present in solution and with its polymer, poly-β-CD. With these modified electrodes, analyses were performed to understand the effect of such surface modifications on the electrochemical response of the analyte dopamine, which was surface-immovilized through formation of the said inclusion complex, as evidenced by the adsorption process that controlled the overall reaction rate of the oxidation process.