Study on the relations between homodynamic parameters and structure of common carotid artery among the Ethnic She Population, China

Abstract

To study the changes of intima-media thickness (IMT) in ambi-common carotid arteries (ambi-CCA) and how they correlated with factors related to quality intima-media thickness (QIMT). According to the Chinese Arterial Stiffness Evaluation (CASE) project, the IMT of (ambi-CCA) was measured by QIMT and 2-D ultrasound respectively in 433 She people aged 15 - 87 (mean 49.03 ± 13.54). Difference and tendency were analyzed on age, gender, body mass index (BMI), pulse pressure (PP), total cholesterol (TC), and triglyceride. The whole population was classified into 3 groups by tertiles of pulse pressure. (1) Significant positive correlations were found between ambi-CCA IMT and pulse pressure (P < 0.01). There was no significant difference between tertile1 and tertile 2 of IMT in the left CCA (P > 0.05) found, but with significant difference among the tertile groups, respectively (P < 0.05). There were significant differences among the three groups of IMT in the right CCA, respectively (P < 0.01). (2) The regression factors of IMT in left CCA were age, pulse pressure, weight, LDL-C, blood glucose (BG), TG, and their regression equation was LCC-IMT = 32.61 + 4.29 (age) + 1.77 (PP) + 1.87 (weight) + 16.52 (LDL-C) + 11.77 (BG) - 9.92 (TG), with r = 0.663 and r(2) = 0.44, (P < 0.001). The regression factors of IMT in right CCA were age, PP, height and their regression equation was RCC-IMT = 5.19 (age) + 1.61 (PP) + 2.62 (height) - 219.36, with r = 0.636 and r(2) = 0.41 (P < 0.001). There were differences seen on IMT of CCA in the PP and position and were correlated with age, PP, body weight, LDL-C, BG, TC and body height. The difference of ambi-CCA should be called for attention.