Abstract

This study was conducted to determine the prevalence of Anaplasmosis and efficacy of different antiprotozoal drugs in goats around the Mirpurkhas. A total of 300 goats were examined for the occurrence of Anaplasmosis. Anaplasma marginale was the only species identified from all positive goats and the highest prevalence of Anaplasmosis was recorded in Samaro (30%) and the lowest (8%) in Sindhri, district Mirpurkhas. The overall prevalence of anaplasmosis was recorded at 13.33%. The rate of infection was higher in females (17%) compared to males (9%). The age wise prevalence was recorded 14% in two years of age and 12% in 2 years and above of age. The most prominent clinical features in positive cases of anaplasmosis were recorded increased body temperature, respiration and pulse rate, with loss of condition and icterus. The disease positive animals were divided into four groups; A, B, C and D in order to determine the efficacy of different antiprotozoal drugs. The Imidocarb, Diminazine and Oxytetracycline drugs were administered to A, B and C groups respectively, on the standard dose by the recommendations of manufacturers. While the D group was kept as an untreated positive control. It was observed that maximum efficacy against Anaplasma marginale was achieved by the administration of Imidocarb (80%), followed by Diminazine (60%) and Oxytetracycline (30%). All animals of the infected control group (D) were remained positive and shown the increasing intensity of the infection and one goat was died in control group D due to the severity of the infection. Keywords: Anaplasmosis; Antiprotozoal drug’s efficacy; Goats; Prevalence http://dx.doi.org/10.19045/bspab.2019.80043

Highlights

  • Introduction economical place in Asian agricultureTheGoats are small ruminants and maintain an importance of goats with a variety of especially valuable ecological and different breeds and the degree of theirPublished by Bolan Society for Pure and Applied Biology adaptation is a unique and wide range of distribution throughout the ecosystem [1].About 90% of the world’s goat population is found in developing countries

  • The highest prevalence rate (30%) of anaplasmosis was recorded in Taluka Samaro and the lowest (8%) in Taluka Sindhri (Table 2)

  • Similar results of anaplasmosis in goat agreement with the results reported from were observed by Lee [18], who reported

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Summary

Research Article

Study on the prevalence of anaplasmosis and efficacy of different antiprotozoal drugs in goats at district Mirpurkhas, Sindh –Pakistan. Muhammad Ismail Memon, Riaz Ahmed Leghari, Hamzo Khan Kumbhar, Nazar Ali Korejo, Mujeeb u Rehman Memon, Saeed Ahmed Soomro, Jameela Soomro, Saajida Parveen and Shiva Ram. Study on the prevalence of anaplasmosis and efficacy of different antiprotozoal drugs in goats at district Mirpurkhas, Sindh –Pakistan. Pure and Applied Biology.Vol 8, Issue 2, pp1025-1032.

Thick blood smears
Staining of the blood smears
Therapeutic trials
The age wise prevalence of Anaplasmosis
Findings
The gender wise prevalence rate of

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