Study on the photophysical property of meso-tetra(2-fluorenyl)porphyrin derivatives and their interactions with DNA/HSA biomacromolecules

Abstract

A classical approach is reported to design tetra-substituted porphyrins and corresponding transition metal Zn(II) derivative. These porphyrins were characterized by HRMS mass analysis, UV–Vis absorption, immobilization and time-resolved fluorescence emission, theoretical DFT calculations, and electrochemical techniques. Photobiological parameters such as photostability and singlet oxygen-producing species were also assessed. Finally, spectroscopic and viscometer studies and molecular docking calculations revealed the ability of each porphyrin derivative to interact with calf thymus DNA and human serum albumin.