Study On The Efficacy Of Peronema Canescens Jack. Leaves As An Immunomodulator Used In Traditional Medicine

Abstract

Introduction:The Sungkai plant (Peronema canescens Jack) is widely used as an immunostimulant.. Sungkai (Peronema canescens Jack.) is one of the leading export commodities, especially for the Sumatra and Kalimantan regions. Sungkai leaf (Peronema canescens Jack.) is a natural source of flavonoids. Objective: To find out the efficacy of sungkai leaves so that they can be used as traditional medicine for the community. Methods: Literature Review. Data sources come from research journals on the efficacy of sungkai plants that can improve the body's immune system from various national and international sources. The data search strategy used was to search directly for gray literature through the Google search engine and use the Google Scholar, Pubmed and Science Direct databases with the keywords “Peronema canescensPlant”, “Traditional Medicine”, or “Efficacy of Sungkai Leaf”. Inclusion criteria included national journals on the efficacy of sungkai plants with Sinta accreditation 1-6, and Scopus-indexed international journals with rankings Q1-Q4. Exclusion criteria include journals that are not focused on discussing the efficacy of sungkai plants, unaccredited journals, and research journals with review methods. Results: From the national and international journals that have been reviewed, it was found that the sungkai plant has efficacy as an immunostimulant, in fertility, and has been tested for safety in pre-clinical animal tests and for generations by the community. Conclusion:Based on the literature that has been collected, it can be concluded that there are many studies on sungkai leaf extracts that are effective in maintaining endurance and have proven safety.