Abstract
BackgroundFoldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1-year follow-up.MethodsA retrospective analysis was conducted for 20 patients with severe ocular trauma or silicone oil (SO) dependent eyes underwent vitrectomy and FCVB implantation in a 1-year follow-up. All treated eyes were peformed clinical examinations involved the visual acuity (VA) examination, Goldmann applanation tonometer, noncontact specular microscopy, fundus photography, B-Scan examination and optical coherence tomography (OCT). The groups were compared with t-test and the McNemar - Bowker test.ResultsIn 1-year follow-up, 20 eyes were evaluated in the study. FCVB well supported the vitreous retina in all treated eyes, and 6 treated eyes achieved retinal reattachment 12 months after FCVB implantation. There were no significant differences in VA before and after FCVB implantation (P = 1.000). In addition, the postoperative IOP markedly elevated from the preoperative IOP of 12.90 ± 7.06 mmHg to 15.15 ± 3.36 mmHg (P = 0.000017). The intraocular pressure (IOP) of 10 eyes maintained at a normal level after surgeries. The other 10 eyes showed slightly lower IOP within the acceptable level. Though two patients developed keratopathy and ocular inflammation respectively, other treated eyes were symmetric with fellow eyes showing satisfactory appearance. Moreover, there was no SO emulsification or leakage happened in the observation.ConclusionsFCVB implantation was an effective and safe treatment in the eyes with severe retinal detachment.
Highlights
Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment
It was designed to refine the way that silicone oil (SO) work in the inner cavity of eyeball, and help to support the retina
Study design A retrospective study of 20 cases involving 20 patients with FCVB implantation was conducted between September 2017 and September 2018
Summary
Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. Over 80% of the structure of the eyeball is natural vitreous body, which contains only 1% of proteins, hyaluronan, lipids and inorganic chemical compounds. Zhang et al BMC Ophthalmology (2019) 19:260 been proved to be toxic for ciliary body and attribute to emulsificate in the eyeball, though SO has the most stable physical and chemical attributions among all the vitreous substitutes [15]. Researchers have been working hard to find suitable vitreous substitutes in the past decades before the invention of FCVB [12, 16]. It was designed to refine the way that SO work in the inner cavity of eyeball, and help to support the retina. Unlike SO tamponade, there is no more need for patients to keep prone positions after surgeries [20]
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