Abstract
Bleeding and infection can cause significant increases in mortalities. Hydrogel sealants have attracted extensive attention for their ability to control bleeding. In this study, the adjuvant treatment with antibacterial adhesive hydrogel dressings was applied to patients with deep second-degree burns/scalds. The traditional medical dressing was regarded as control adjuvant treatment. The results indicated that the total positive rate of bacteria in wound secretions and the pain during dressing change in patients who used antibacterial adhesive hydrogel dressings were significantly reduced. The number of fibroblasts and new capillaries in the granulation tissue of the wound increased, and the patient's wound healing is accelerated. The overall clinical effectiveness has been significantly improved. It is proven that the antibacterial adhesive hydrogel dressing has a significant effect on wound healing.
Highlights
The skin is the human body’s largest natural barrier, which keeps the internal environment stable and protects tissues and organs from chemical substances and physical and pathogenic microorganisms [1]
The clinical efficacy of the patients was evaluated after 2 weeks of treatment: invalid: there is no change in the wound, or the wound area is smaller than 25%
Hydrogel-based hemostatic materials have drawn significant attention in recent years because they act as sealants to control bleeding [1, 3, 6, 7], which provides a barrier against infection by microorganisms [4, 8, 9] and creates a suitable microenvironment for accelerated wound healing
Summary
The skin is the human body’s largest natural barrier, which keeps the internal environment stable and protects tissues and organs from chemical substances and physical and pathogenic microorganisms [1]. Wound treatment is still challenging in special areas because of inevitable movements and difficult fixation [3,4,5,6] To this end, designing a stretchable, adhesive, antibacterial, and biocompatible dressing is of great clinical significance. Pathogenic bacterial infection is the main reason contributing to the impediment of wound healing To address this issue, many studies have set to explore adhesive hydrogels with antibacterial effects on animals [12]. This study mainly concentrated on patients with deep second-degree burns/scalds as experimental subjects and attempted to explore the effect and specific mechanism of antibacterial adhesive hydrogel on promoting wound healing in patients, to provide a reference for clinical treatment of deep second-degree burns/scalds
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Computational and mathematical methods in medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
