Study on the direct analysis of solid powder biological samples using fluorination assisted electrothermal vaporization inductively coupled plasma atomic emission spectrometry with PTFE slurry modifier

Abstract

A method has been described for the direct determination of Ti, Cu, Mn, Cr and Cd in solid biological samples without any chemical pretreatment by fluorination assisted electrothermal vaporization inductively coupled plasma atomic emission spectrometry (ETV-ICP-AES) with slurry sampling. A polytetrafluorethylene (PTFE) emulsion was used as a fluorinating reagent to promote the vaporization of the analytes from the graphite furnace. The interface between furnace device and ICP torch and the main factors affecting the analytical signal were investigated systematically. The detection limits for the determination of Ti, Cu, Mn, Cr and Cd are 6.3, 4.7, 10, 13 and 278 ng/mL, respectively; the relative standard deviations are in the range of 1.5 (Mn) ∼4.0% (Cd) after optimization of the operating conditions. The recommended approach has been applied to directly determine the trace elements of interest in the Chinese traditional medicine Loulu and in the solid biological standard reference material (peach leaves, GBW 08501) with satisfactory results.