Study on the correlation analysis and the mechanism of PCT, CRP level and the puerperal infection after cesarean section

Abstract

Objective To investigate procalcitonin (PCT) and C reactive protein (CRP) expression in patients with puerperal infection after cesarean section and its clinical significance. Methods From January 2014 to January 2016, 134 cases of cesarean section puerperal infection patients in our hospital were enrolled in observation group, according to 1∶3 matching, we selected 402 cases of cesarean section without puerperal infection as the control group. Then the levels of PCT and CRP in two groups were detected. Results CRP and PCT levels of 24 h, 48 h and 72 h of the patients in the observation group were (13.16±1.06)mg/L and (1.05±0.42)g/L, (15.15±1.50)mg/L and (1.67±0.31)g/L, (16.01±2.32)mg/L and (2.10±0.92)g/L respectively, significantly higher than the control group (P<0.05); 72 h CRP and PCT levels of pelvic cavity peritonitis patients were (17.13±1.46)mg/L and (2.81±0.97)g/L respectively, significantly higher than that in patients with vulvovaginal and cervicitis, endometritis and fallopian tube (P<0.05); 72 h CRP and PCT in patients with endometritis and fallopian tube inflammation were (15.89±1.06)mg/L and (2.06±0.83)g/L, significantly higher than that of vaginal and Cervicitis Patients (P<0.05). Conclusions CRP and PCT increase rapidly in patients with puerperal infection after cesarean section, and there are a certain relationship with puerperal infection disease and they are of certain clinical application value. Key words: Cesarean section/CO; Puerperal infection/CO/ME; Calcitonin/ME; C-reactive protein/ME