Study on the application of embolization materials of collagen

Abstract

The embolization mechanism, advantages and disadvantages as well as clinical application of collagen embolization materials were retrospectively analyzed, and the correlation between their application fields and the selection of embolization materials was discussed, so as to provide references for clinical treatment. Relevant literatures in Pubmed and Web of Science databases were searched, and the literature on clinical application and experimental research of embolic materials was systematically evaluated. Embolic materials should be biodegradable and biocompatible. Embolic materials for clinical use include absorbable gelatin sponge, polyvinyl alcohol particle embolization agent, micro-spring coil and liquid embolization materials. Gelatin embolization materials have the advantages of non-antigenicity, histocompatibility, convenient preparation, excellent compressibility and expansion in water. Endovascular embolization materials have been produced and applied in clinical practice, but new problems and new requirements have been rising. All kinds of embolic materials have advantages and disadvantages, and none of them can be suitable for all diseases. Therefore, it is very important to select suitable embolic materials for safe and effective treatment.