Abstract

Silk fibroin (SF) was regenerated for electrospinning. A mixture solvents Trifluoracetic acid (TFA) and dichloromethane (DCM) was selected as the solvent of regenerated SF. Its spinning properties and characteristics of end nanofibers mats were compared with those of the regenerated SF electrospinning solution dissolved in formic acid (FA). From the comparison of SEM images of regenerated SF electrospinning from the two different solvents solutions, it could be found that the spinning concentration range in TFA&DCM was smaller than that in FA for the solution viscosity was bigger than that in FA. Moreover, from the FTIR spectra of electrospun nanofibers obtained from TFA&DCM and FA was both similar with that of regenerated SF. This meant that there was no new group formed when TFA& DCM was selected as solvents. Therefore, TFA&DCM were also a nice option for the electrospinning of regenerated SF.

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