Study on risk factors of ventilator-associated pneumonia

Abstract

Objective To investigate the risk factors of ventilator-associated pneumonia in Intensive Care Unit (ICU) patients. Methods A total of 120 patients admitted to ICU of this hospital with invasive ventilator for mechanical ventilation from January 2016 to July 2017 were selected as research objects.According to whether they developed ventilator related pneumonia, they were divided into study group and control group.There were 62 cases of ventilator associated pneumonia in the study group and 58 cases in the control group.The relevant clinical parameters of patients during treatment were recorded, including biochemical index APACHE score for drug use and intubation time. Results Among all patients, there were 52 cases of VAP, 15 cases of early-onset VAP and 47 cases of late-onset VAP.Compared with the control group, the research group was significantly better than of the control group in terms of APACHE score and Glasgow score, with statistically significant differences(P<0.05). Logistic regression results showed that, the age of patients with longer mechanical ventilation time and longer stay in coma, the use of glucocorticoids, acid-inhibiting agents and antibiotics were important risk factors for the development of VAP. Conclusion If patients with invasive ventilator mechanical ventilation do not take scientific preventive measures, it will lead to the occurrence of ventilator-associated pneumonia and even death.The main risk factors of ventilator-associated pneumonia are the older age, mechanical ventilation time and prolonged hospital stay, and the failure to use antibiotics scientifically.Therefore, effective measures can be taken for risk factors, and corresponding preventive measures can be proposed to improve the clinical treatment effect of patients. Key words: Ventilator-associated pneumonia; Mechanical ventilation; Risk factors