Study on relationship between general psychopathology and relapse in opioids dependence under treatment on methadone maintenance therapy, Kerman, Iran, 2014

Abstract

Introduction Performed studies indicate association between drug abuse and other mental disorders. Mental disorders could be effective in response to treatment and also, accession of recurrence process in addiction treatment course. Methods and materials This research is causal – comparative and of cross-sectional type was performed in 2014 on 200 drug abusers under methadone maintenance treatment (in two groups, with relapse in treatment process and without relapse) in drug rehabilitation centers of Kerman city. Questionnaire which includes demographic features and BPRS test was completed. Data were processed by suitable statistical methods via SPSS20 and SAS9.1 software. Findings Results obtained from the research showed that the acquired scores average from BPRS test is more in relapsing group ( P P =0.030), anxiety ( P P P =0.003), hostility ( P P =0.008), suspiciousness ( P =0.024), hallucination ( P =0.009), blunted affect ( P =0.030), tension ( P =0.012), uncooperativeness ( P =0.011), excitement ( P =0.038) and emotional withdrawal ( P =0.019) in two abuser groups had significant difference (more in relapsing group). No significant difference was observed between subscales of unusual thought content, disorientation, conceptual disorganization, mannerism and posturing and motor retardation in two groups ( P >0.05). In patients with more relapse in treatment process, score of BPRS is higher ( P Conclusion Findings of this study showed that intensity of psychiatric disorders in relapsing drug users is more than non-relapsing users and with growth of disorders intensity, the number of recurrence increases.