Study on pressure control and energy saving of cleanroom in purification air conditioning system

Abstract

Pressure control for cleanrooms in the pharmaceutical industry is a necessary means to avoid the cross-contamination. The pressure control of traditional air conditioning can only handle the working stage. In the non-working stage, the system cannot reduce the air change rate per hour (ACH) in order to alleviate the problem of high energy consumption. This paper proposes an improved air conditioning system, which focuses on the ability to control pressure gradient of the system in working and non-working mode. By theoretical derivation of the combined fan frequency conversion, when the impedance and volume of the infiltration air satisfy SiGZ,i=SjGZ,j=SkGZ,k=constant, the pressure gradient in multi-zone cleanrooms can remain stable. A mathematical model of the system has been established, which includes five modules: air pipe network, fan characteristic curve, fan operating point solution, variable volume damper characteristic curve and multi-zone network pressure gradient solution. The correctness of the model is verified by field measurements. Taking a clean workshop as case study, the room pressure can be stabilized in the range of ± 3 Pa by switching the working and non-working mode, which can save 39.8% of the energy consumption in non-working mode, while ensuring cleanliness. This paper demonstrates the process of the air pipe network’s influence on cleanrooms pressure and proves the effectiveness of improved purification air conditioning system in pressure gradient control and energy saving potential.