STUDY ON PRE-HYPERTENSION PREVALENCE AND RELATIONSHIP WITH DYSLIPIDEMIA IN ADULTS AT QUANG NAM PROVINCE

Abstract

Objectives: To investigate the prevalence, risk factors of prehypertension in QuangNam province of Vietnam. Methods: A case-control study of 3.237 adults (aged ≥ 25 years) was conducted in Quang Nam province, Vietnam in 2017, using questionnaire interviews, clinical examinations, and laboratory tests. Blood pressure, anthropometry, plasma glucose and lipids were measured. The variables contributing significantly to pre-hypertension were analyzed by multiple logistic regression analysis. Results: The prevalence of prehypertension, hypertension and normal blood pressure was 30.7%, 31.6% and 37.7%, respectively. Cardiovascular risk factors such as overweight and obesity, family history of hypertension, alcohol abuse, smoking, diabetes, high total cholesterol levels, high triglyceride levels, high LDL-C levels were significantly greater in prehypertensive compared to optimal blood pressure (BP). Multivariable logistic regression analysis revealed strong positive associations of pre-hypertension with alcohol abuse (OR = 1.68; CI 95%: 1.29-2.20; p < 0.001), diabetes (OR = 3.39; CI 95%: 1.32 - 8.65; p=0.011); high triglyceride levels (OR = 1.41, CI 95%: 1.13 - 1.75, p = 0.002); high LDL-C levels (OR = 1.42; CI 95%: 1.03 - 1.97; p=0.034). There was a positive correlation of cardiovascular risk factors such as BMI, abdominal circumference, blood glucose, blood cholesterol, blood triglyceride, blood LDL-C with changes in systolic BP, diastolic BP, and average BP. Conclusions: The prevalence of prehypertension in Quang Nam province of Vietnam was 30.7%. Risk factors such as alcohol abuse, diabetes, high triglycerides, high LDL-C were significantly associated with prehypertension. Key words: cardiovascular risk factors - hypertension – prehypertension