Abstract

Aim of the study: The aim and objective of the present study was, to enumerate and evaluate different types of pre-analytical errors in the clinical biochemistry laboratory and to compare the frequency of errors in the pre-analytical phase of testing before and after training the technical staff posted in the clinical biochemistry laboratory. Materials and methods: A prospective Study was conducted at Dept. of Biochemistry, CIMS, Bilaspur. Chhattisgarh Institute of Medical Sciences, a tertiary care hospital cum medical college in Bilaspur for the period of 4 months from August 2016 to December 2016. During this period, different types of pre-analytical errors were monitored. Results: Of the 19,411 samples received during the study period, 670 samples were found to be unsuitable for testing, accounting for 3.45% of the rejection. All these samples were rejected due to different types of pre-analytical errors that are due to wrong identification (0.26%), missing samples (0.05%), draw from IV site (0.07%), inadequate samples (1.02%), wrong timing of sample collection (0.06%), hemolysed samples (1.83%) and lipemic samples (0.28%). Conclusion: Of all the samples received in the clinical biochemistry laboratory, the overall percentage of rejection is 3.45%. We also found that, there was reduction in the frequency of errors before and after training the staff.

Highlights

  • Central Clinical Laboratory is the backbone to the hospital set up, as it contributes significantly in making the right diagnosis to the right patient at right time and the right treatment, which affects the duration of hospital stay, early treatment response and the well-being of the patient

  • Of the 19,411 samples received during the study period, 670 samples were found to be unsuitable for testing, accounting for 3.45% of the rejection

  • All these samples were rejected due to different types of pre-analytical errors that are due to wrong identification (0.26%), missing samples (0.05%), draw from IV site (0.07%), inadequate samples (1.02%), wrong timing of sample collection (0.06%), hemolysed samples (1.83%) and lipemic samples (0.28%)

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Summary

Introduction

Central Clinical Laboratory is the backbone to the hospital set up, as it contributes significantly in making the right diagnosis to the right patient at right time and the right treatment, which affects the duration of hospital stay, early treatment response and the well-being of the patient. Modern day medicine practice is purely evidence based which focuses on the valid laboratory reports for the effective and timely management of patients [1]. Laboratory testing involves mainly three phases: 1) Pre-analytical phase 2) Analytical Phase and 3) Post-analytical phase. The preanalytical phase encompasses all the processes from the time of a laboratory request made by the physician until the specimen is analyzed in the lab (e.g. patient preparation, blood drawing, sample transportation, centrifugation, dilutions etc.). The analytical stage involves the analysis of the analytes using automation especially in clinical biochemistry laboratory and validation of the test results. The post-analytical stage refers to the interpretation of the results by laboratory consultants and reporting to the clinicians via printed reports [2]

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