Abstract

The typical inverse ECG problem is to noninvasively reconstruct the transmembrane potentials (TMPs) from body surface potentials (BSPs). In the study, the inverse ECG problem can be treated as a regression problem with multi-inputs (body surface potentials) and multi-outputs (transmembrane potentials), which can be solved by the support vector regression (SVR) method. In order to obtain an effective SVR model with optimal regression accuracy and generalization performance, the hyperparameters of SVR must be set carefully. Three different optimization methods, that is, genetic algorithm (GA), differential evolution (DE) algorithm, and particle swarm optimization (PSO), are proposed to determine optimal hyperparameters of the SVR model. In this paper, we attempt to investigate which one is the most effective way in reconstructing the cardiac TMPs from BSPs, and a full comparison of their performances is also provided. The experimental results show that these three optimization methods are well performed in finding the proper parameters of SVR and can yield good generalization performance in solving the inverse ECG problem. Moreover, compared with DE and GA, PSO algorithm is more efficient in parameters optimization and performs better in solving the inverse ECG problem, leading to a more accurate reconstruction of the TMPs.

Highlights

  • The inverse ECG problem is to obtain myocardial transmembrane potential (TMPs) distribution from body surface potentials (BSPs), noninvasively imaging the electrophysiological information on the cardiac surface [1, 2]

  • We focus on implementing the reconstruction of transmembrane potentials (TMPs) from BSPs

  • This study introduces three optimization methods (GA, differential evolution (DE), and particle swarm optimization (PSO)) to determine the hyperparameters of the support vector regression (SVR) model and utilizes these models to reconstruct the TMPs from the remote BSPs

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Summary

Introduction

The inverse ECG problem is to obtain myocardial transmembrane potential (TMPs) distribution from body surface potentials (BSPs), noninvasively imaging the electrophysiological information on the cardiac surface [1, 2]. An alternative method, support vector regression (SVR) method [7], was proposed to solve the inverse ECG problem. The above mentioned optimization algorithms (GA, DE, and PSO) are all adopted to dynamically optimize the hyperparameters of SVR model in solving the inverse ECG problem. We attempt to investigate which one is the most effective in reconstructing the cardiac TMPs from BSPs, and a full comparison of the performance for solving the inverse ECG problem will be evaluated

Theory and Methodology
The Proposed System Framework
Preprocessing the Data Set
Method DE
Conclusion
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