Abstract
690 Background: Lymph node, peripheral blood, and bone marrow are frequently transferred by breast cancer cells. Micrometastases in lymph node, peripheral blood, and bone marrow are difficult to be found by conventional histological examination. We first detected micrometastases in bone marrow by the method of immunohistochemistry(IHC) in 1989. It had significant correlation with patients' prognosis. In this study, several methods were used to study on the micrometastases in sentinel lymph node(SLN), peripheral blood, and bone marrow from the same breast cancer patients. Methods: Continuous slices, IHC and RT-PCR assays were used to detect micrometastases in SLN, peripheral blood and bone marrow from breast cancer patients. These samples were collected from 38 patients, with no palpable lymph node preoperatively, performed sentinel lymph node biopsy (SLNB) by 1% isosulfan blue and pathologically diagnosed negative under HE staining. Results: Of the 38 paired bone marrow and peripheral blood samples, 11 bo...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
