Study on infection condition of chlamydia trachomatis and ureaplasma urealyticum in patients with cervical erosion

Abstract

Objective To investigate the current situation of infection of chlamydia trachomatis (CT) and ureaplasma urealyticum (UU) in patients with cervical erosion,and explore the relationship between the infection of CT and UU and cervical erosion.Methods Immunochromatography and culturing method were used to detect the cervical secretion obtained from 562 cases of cervical erosion patients (the observation group) and 218 healthy controls (the control group) for the CT and UU.The drug susceptibility testing was performed for the patients' with mycoplasma tested positive.Results In the observation group,the positive rates of CT,UU and both were 20.11％,42.35％ and 9.61％ respectively,which were higher than 6.42％,12.39％ and 0.92％ in the control group,the difference was significantly different (P ＜ 0.05).The difference of the positive rate between moderate cervical erosion and severe cervical erosion was not significantly different (P ＞ 0.05),while the positive rates of CT,UU and both were significantly different (P ＜ 0.05) when mild cervical erosion respectively compared with moderate cervical erosion and severe cervical erosion.The highest susceptibility rate of UU to 9 kinds of antimicrobial agents was josamycin (91.78％),the second was pristinamycin (84.25％); the highest resistant rate of UU was ciprofloxacin (85.96％),the second was ofloxacin (73.29％).Conclusion The infection of CT and UU has intimate correlation with the occurrence of cervical erosion and the extent of erosion.Varying degrees of drug resistance of UU can be found in clinical common use antibiotics,and the sensitive and effective antibiotics should be chosen to treat cervical erosion infection of UU. Key words: Cervical erosion; Chlamydia trachomatis; Ureaplasma urealyticum; Infection; Drug susceptibility testing