Abstract
The solidification time of injectable bone cement should be fit for the clinical application. This research find out the effect of the amount of water-absorbent agent and water-retaining agent. The optimal ratio was be determined. The hydroxyapatite fibers with strontium were added into the CPC. The mechanical property, cytotoxicity test, SEM morphology, XRD and degradation performance in vitro were characterized, respectively. The results show the CPC had the solidification time of 12min when the ratio as below: β-TCP 55.5%, Ca (H2PO4)2H2O(MCPM)36%, MgHPO43H2O 5%, MgSO41%, Sodium pyrophosphate2.5%. The main components of solidify CPC were hydroxyapatite (HA) and dicalcium phosphate dihydrate (DCPD). The materials had a good Anti-collapsing performance and the degradation rate up to 16.72% after 9 weeks. The mechanical property of composite materials which combined with hydroxyapatite fibers with strontium has been improved, and the cell proliferation rate is also higher than common CPC. This study shows a potentially effective method to improve the mechanical property and the biological activity of calcium phosphate cement.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
