Abstract

Background and purposeDrug costs is one of the main components of hospitalization expenditure for cerebral infarction inpatients. In China, the National Essential Medicine System (NEMS) was created to relieve the heavy drug-cost burden for patients. The objective of this study was to investigate essential drug-use status and its influencing factors among cerebral infarction inpatients in county-level hospitals of Anhui province, China.MethodsThree county-level hospitals were selected through a multi-stage cluster random sampling method. The hospitalization cost data of cerebral infarction inpatients in the three hospitals were extracted from the Anhui provincial information platform of the New Rural Cooperative Insurance System (NCMS), and whether the proportion of essential drug cost in the total drug cost reached the median value of 33.05% which was set as the evaluation index for essential drug-use status. Questionnaires for hospitals and physicians were designed and given to them to assess influencing factors.ResultsWe retrieved the cost data of 2,189 inpatients from the NCMS platform and investigated 51 corresponding physicians in total. The drug costs accounted for 52.6% of the total hospitalization cost, and essential drug costs alone accounted for 37.0% of the total drug costs. The essential drug-cost proportion was high among physicians with a higher recognition degree on NEMS, older age, lower final academic degree, longer work experience and lower professional title. Married physicians and those with tight organizational affiliation also prescribed more essential drugs.ConclusionsIncreasing the proportion of essential drugs was an effective way to reduce the disease burden for cerebral infarction patients. Perfecting the NEMS, increasing government investment, reinforcing education and propaganda, and formulating relevant incentive and restrictive mechanisms were all effective ways to promote and increase the number of essential drug prescriptions written by physicians.

Highlights

  • Stroke is the leading cause of disability and the second leading cause of death worldwide [1]

  • The hospitalization cost data of cerebral infarction inpatients in the three hospitals were extracted from the Anhui provincial information platform of the New Rural Cooperative Insurance System (NCMS), and whether the proportion of essential drug cost in the total drug cost reached the median value of 33.05% which was set as the evaluation index for essential drug-use status

  • The essential drug-cost proportion was high among physicians with a higher recognition degree on National Essential Medicine System (NEMS), older age, lower final academic degree, longer work experience and lower professional title

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Summary

Introduction

Stroke is the leading cause of disability and the second leading cause of death worldwide [1]. Cerebral infarction, caused by blockage of an artery supplying blood to the brain [2], accounts for about three quarters of all stroke cases [3, 4]. It has the characteristics of high morbidity, high mortality and high recurrence, and has a trendency of striking younger people. Patients under 45 years old account for nearly 15% of all the cases [7] This disease has already produced a heavy direct and indirect economic burden for the whole nation. The objective of this study was to investigate essential drug-use status and its influencing factors among cerebral infarction inpatients in county-level hospitals of Anhui province, China

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