Study on clinical application of susceptibility weighted imaging ombined with diffusion weighted imaging in patients with Liver Cirrhosis complicated with small Hepatocellular Carcinoma.

Zhi-Bo Hou,Chun-Zhu Zhang,Fei Zhao,Bin Zhang

doi:10.12669/pjms.37.3.3822

Abstract

Objectives:To evaluate the clinical value of susceptibility weighted imaging (SWI) combined with diffusion weighted imaging (DWI) in patients with liver cirrhosis complicated with small hepatocellular carcinoma (SHCC).Methods:A total of 40 patients with liver cirrhosis and 44 nodules were treated with conventional nuclear magnetic scanning (T1WI, T2WI) and SWI combined with DWI; the results were judged by two senior physicians; the t test, χ2 test, rank sum test, and other methods were used for contrastive analysis of the pathological results of different scanning methods after operation or puncture.Results:Contrast analysis of the different MRI scanning methods and pathological results showed that among the 32 nodules of small hepatocellular carcinoma, 24 cases were diagnosed by conventional MRI, with the coincidence rate being 75%, 30 cases were diagnosed by SWI DWI, with the coincidence rate being 96%; significant difference was found between the two groups (p=0. 04). Significant differences were found in the specificity, sensitivity and accuracy of different scanning methods in the diagnosis of small hepatocellular carcinoma (specificity, accuracy, p=0.04; sensitivity p=0.01). The SWI of small hepatocellular carcinoma nodules showed hyperintensity, and the degree of iron deposition was low. Significant difference was found between small hepatocellular carcinoma nodules and other nodules (comparison of SWI signal degree, p=0.01; comparison of iron deposition degree, p=0.00).Conclusion:The SWI of small hepatocellular carcinoma nodules showed hyperintensity, and the degree of iron deposition was low. The coincidence rate of SWI+DWI scanning is higher than that of conventional scanning methods in the diagnosis of small hepatocellular carcinoma, and the difference in specificity, sensitivity and accuracy has obvious advantages. SWI+DWI scanning can improve the detection rate of liver cirrhosis complicated with small hepatocellular carcinoma.

Highlights

Liver cirrhosis is a common chronic disease in digestive system, which is mostly caused by hepatitis B virus infection.[1]
susceptibility weighted imaging (SWI)+diffusion weighted imaging (DWI) scanning can improve the detection rate of liver cirrhosis complicated with small hepatocellular carcinoma
Among the 32 nodules of small hepatocellular carcinoma, 24 cases were diagnosed by conventional MRI, the coincidence rate was 75%, 30 cases were diagnosed by SWI DWI, the

Summary

Introduction

Liver cirrhosis is a common chronic disease in digestive system, which is mostly caused by hepatitis B virus infection.[1] In the advanced stage, it gradually develops into hepatic encephalopathy, upper gastrointestinal hemorrhage, carcinogenesis and so on, which causes great harm to the patients. Pak J Med Sci May - June 2021 Vol 37 No 3 www.pjms.org.pk 800. Primary hepatic carcinoma is one of the most serious complications in patients with liver cirrhosis.[2] Early diagnosis is of great importance for the treatment effect and prognosis of patients. KWON’s study showed that.[3] iron deposition occurred in noncancerous nodules before carcinogenesis after cirrhosis of liver, and iron deposition in nodules after carcinogenesis gradually decreased

Objectives

Methods

Results

Conclusion