Study on Antimicrobial Activity of Chromolaena odorata and Aerva lanata

Abstract

Purpose: Numerous natural products from traditional medicinal plants have extensive chances for new steers to drug development because of the obtainability of chemical diverseness. Advanced modern methods are developed for the extraction, which are pointed to be the critical move in formulation of plants. These latest approaches of extraction are more effectual than the antient extraction methods for the effective development of traditional herbal remedies. For the greater extraction and study of medicinal plants, scientists prefer modern sample- preparation techniques over conventional techniques as they ensure the better-quality herbal products to the worldwide consumers. The interest in plant based therapeutic drugs and comestible plants has grown all over the World, since the increase in stipulation for chemical diverseness in investigation programs. Design/Methodology/Approach: The study examines how different plant extract concentrations and extraction solvents affect the antimicrobial activity of several therapeutic plants. The traditional mechanical method is used for extraction. Chromolaena odorata and Aerva lanata were the medicinal plants chosen for the extraction. Different concentrations of the extracts were made such as 1%, 10% and 50%. Diethyl ether, sterile distilled water and ethanol are the solvents used for extraction. Two common techniques were used to observe whether the selected plants have any antimicrobial activity against the organisms, which were agar disc diffusion and well diffusion method. Klebsiella pneumonia, Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus Staphylococcus aureus were the microorganisms selected for this study. Findings/Result: Among the selected extracts, aqueous extract gave more activity against infectious microbes. C. odorata showed better reaction with S. aureus, K. pneumonia and B. subtilis, were as A. lanata found well reactive against P. aeruginosa, S. aureus and K. pneumonia. Originality/Value: This study gives us an outline about the antimicrobial activity of C. orodata and A. lanata on various infectious microbes, based on the collected data. Paper type: Case study based research approach.