Study on analgesic of dezocine combined with different doses of butorphanol for postoperative patient-controlled intravenous analgesia after lower limbs surgery

Abstract

Objective To study on analgesic of dezocine combined with different doses of butorphanol for postoperative patient-controlled intravenous analgesia (PCIA) after lower limbs surgery.Methods Ninety patients (20-55 years of age,ASA class Ⅰ or Ⅱ) undergoing orthopaedic lower limbs surgery were randomly allocated into three groups with 30 cases each.The patients in group A received 0.2 mg/kg dezocine and 0.14 mg/kg butorphanol,in group B received 0.2 mg/kg dezocine and 0.16 mg/kg butorphanol,in group C received 0.2 mg/kg dezocine and 0.18 mg/kg butorphanol for PCIA.Observed the VAS scores,Ramsay scores after operation for 2,4,8,12,24 h,the times of PCIA and adverse reaction,calculated the degree of satisfaction.Results Adequate analgesia and sufficient sedation were achieved in group B and group C.The VAS scores and Ramsay scores in group B and group C were better than those in group A after operation for 4,8,12 h (P ＜ 0.05).The times of PCIA was requested more often in group A than that in group B and group C after operation for 4,8 h (P ＜ 0.01).The incidence of excessive sleep in group C was more often than that in group A and group B.The comprehensive satisfaction in group B and group C was higher than that in group A (P ＜ 0.01).Conclusion 0.2 mg/kg dezocine combined with 0.16 mg/kg butorphanol is good for postoperative PCIA after lower limbs surgery. Key words: Dezocine; Butorphanol; Orthopaedic ; Analgesia, patient-controlled