Study of Vitamin D level in children with Non-specific Musculoskeletal Pain

Abstract

BackgroundVitamin D deficiency is known as a one of the underlying causes of Idiopathic musculoskeletal pain (IMSP). This study aimed to evaluate the correlation between serum vitamin D (Cholecalciferol) status in patient with Non-specific Musculoskeletal Pain and healthy children.Materials and MethodsSeventy-seven children (aged 3–14 years), with IMSP were included as cases and 90 healthy subjects were selected for control group. Demographic characteristics and biochemical levels of vitamin D and Parathyroid hormone (PTH), were obtained. Data were analysis using SPSS version 17.0 software.ResultsResults showed that vitamin D means levels of patients and healthy children were significantly different (19.5 + 8.84 ng/mL versus 12.7 + 11.89 ng/mL), respectively (P<0.05). Also, there was a significant difference between PTH level in both healthy and patient subjects (P<0.001). Mean levels of vitamin D in both groups were below the normal range, but lower in control group (P<0.001).ConclusionDeficiency of vitamin D was suggested as the probable identified risk factors for IMSP in children. The results of our study did not reveal clear correlation between vitamin D deficiencies in children which suffer IMSP compared the healthy children.