Study of vaginal microecological imbalance and endometrial receptivity change in the treatment of female infertility

Abstract

Objective—To understand the relationship between vaginal microecology and endometrial receptivity, and to explore the clinical effect of adjusting vaginal microecology and improving endometrial receptivity in the treatment of female infertility. Study Design—A total of 60 patients with vaginal microecological disorders and poor endometrial receptivity were selected and randomly divided into two groups. The drug treatment group (n = 30) was treated with lactobacillus preparation for 3 months, and the control group (n = 30) was not treated. Three months later, vaginal microecology and endometrial receptivity were detected again by ultrasound. Results—In the drug treatment group, there were significant differences in pH, density, diversity, vaginal flora, cleanliness, PI, endometrial thickness and endometrial type before and after treatment (P < 0.05).The predominance of Lactobacillus in the vagina can be restored by using Lactobacillus preparations. The application of vaginal Lactobacillus preparation is beneficial to improve endometrial receptivity.