Study of toxic metal pollution in autistic patients in Thi-Qar Governorate

Abstract

Background. Autism-spectrum disorders (ASDs) are a group of chronic neurodevelopmental conditions characterized by difficulties in social interaction and communication, as well as rigid thinking and behavior. Aim of this study. This study aimed to examine the potential impact of trace metals, specifically copper, iron, and zinc, in the development of autism spectrum disease. Materials and method. A total of 100 blood samples were collected from patients diagnosed with autism, while an additional 100 samples were taken from healthy individuals serving as a control group. The individuals separated into three distinct groups: Group A (control) consisted of one hundred healthy participants aged 3-14 years. Group B consisted of one hundred patients diagnosed with autism, ranging in age from 3 to 14 years old. Results. The findings demonstrated a substantial elevation in the levels of lead (Pb), selenium (Se), cadmium (Cd), nickel (Ni), and chromium (Cr) in all groups of patients as compared to the control group. Conclusion. The present study is of the relationship between trace elements and autism. It was observed that the concentration of lead (Pb) and chromium (Cr) was significantly higher in women who did not consume folic acid compared to those who did. On the other hand, the level of nickel (Ni) was significantly lower in women who did not consume folic acid compared to those who did.