Study of Total Intravenous Anaesthesia in laparoscopic Surgery

Abstract

Background: Total intravenous anaesthesia in laparoscopic surgery is safer than open laparotomy operationsbecause propofol, a sedative hypnotic agent with excellent recovery drug and having anti-emetic properties, andnew synthetic opioids (fentanyl congeners) provide excellent analgesia; hence, TIVA has become more popular inlaparoscopic surgery.Method: 45 adult patients aged between 18 to 65 undergoing laparoscopic surgery were studied. A solutionof propofol containing different concentrations of sufentanil (1 μgm per ml and 2 μgmper ml) was infused.Patient’s HR, SBP, DBP, MAP, and peripheral O2 saturation from the anaesthesia monitor was taken as a baselinemeasurement. All the hemodynamic parameters were recorded intra-operatively at different intervals of duration.Results: The changes in mean values of hemodynamic values were insignificant, and only significant parameterswere noted. 158.12 (± 80.9) mean value time to rescue analgesia (in minutes) Post-surgical complications are 3(6.6%) Nausea and vomitingConclusion: Propofol, containing different concentrations of sufentanil, provides hemodynamic stability withthe least post-surgical complications; hence, total intravenous anaesthesia is an ideal substitute for inhalationanaesthesia in laparoscopic surgery because inhalation anaesthesia has a higher risk of hemodynamic instability.