Abstract

Infertility is the inability of a couple to conceive for more than a year of having regular unprotected intercourse. It can be divided into two broad categories - primary and secondary infertility. Primary infertility refers to the inability to ever have a child. Secondary infertility refers to those cases where people have had children but fail to conceive after that. An average estimate suggests that 60-80 million couples suffer from infertility, out of which 15-20 million couples belong to India. Thyroid hormones are essential for normal growth, sexual development and reproductive function. Thus thyroid dysfunctions may have a great impact on fertility in females. Aim: To study the thyroid profile in infertile women. Materials and Methods: A total of 216 subjects comprising of 116 infertile women as cases and 100 age matched healthy euthyroid fertile women as controls were included in the study. Results: Mean serum T3 and T4 were significantly increased (p<0.01), while TSH levels were significantly decreased (p<0.01) in hyperthyroid and reverse was happened in hypothyroid cases when compared to controls. Conclusion: The study indicates association of thyroid dysfunction in infertility. Subclinical thyroid dysfunction was dominant thyroid disease in infertile women. Thyroid profile should be kept in consideration during the diagnosis and management of infertility.

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