Abstract
Protease exhibiting thrombolytic activity was partially purified from the latex of medicinal plant Thevetia peruviana, a yellow oleander with a native name karaveera. The latex collected from the fruit tip of the plant was processed through centrifugation followed by dialysis. Further, partial purification using acetone precipitation indicated the presence of proteins ranging between 15 kDa - 50 kDa. In the present study, the partially purified extract obtained was shown to exhibit proteolytic activity with the capability of thrombus degradation signifying Thevetia peruviana plant latex as a potent clot buster.
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