STUDY OF THE RELATIONSHIP BETWEEN MANIFESTATIONS OF AUTONOMIC DYSFUNCTION AND HYPERTENSION SEVERITY

Abstract

Introduction. Hypertension is one of the most common diseases of the cardiovascular system, which is observed in the majority of the working population of Ukraine and around the world. Autonomic dysfunction syndrome is one of the first manifestations and precursors of hypertension. Materials and Methods. The study included 81 patients with hypertension and autonomic dysfunction. Patients were divided into 3 groups depending on blood pressure. To assess the pathology data, blood pressure was measured according to the 2018 recommendation and patients were surveyed according to a standard questionnaire to identify autonomic disorders by Vein. Results. When assessing the prevalence of symptoms of autonomic dysfunction in the study groups, there was a weak dependence of their occurrence with the severity of hypertension, even in patients with mild hypertension there was a significant frequency of symptoms, which cannot but adversely affect patients' quality of life. Assessing the severity of symptoms of autonomic dysfunction, the prevalence of symptoms such as palpitations, sweating, periodic discoloration of the extremities and paroxysmal headaches in the first group (the most favorable course of high blood pressure). For the second group, the most severe were symptoms such as intermittent numbness of the fingers and shortness of breath. The rank correlation between the degree of hypertension and the severity of autonomic dysfunction was 0.103 (p = 0.302), which indicates a positive correlation between these parameters, but the relationship was weak and did not acquire statistical significance. Conclusion. In patients with a combination of hypertension and autonomic dysfunction, the symptoms of the latter are common at any severity of hypertension. The relationship between the severity of hypertension and autonomic dysfunction could not be established, among hemodynamic indicators, pulse blood pressure was most correlated with the index of autonomic dysfunction.