Study of the possible relations between seminal plasma antisperm antibodies and thyroid function tests in men infertility

Abstract

Infertility is defined as a man in a reproductive age who cannot conceive despite having regular unprotected intercourse for one year. It accounts for 40-50% of infertility in humans. In this study, the patients were gathered in 4 groups: 1. group - Prednisolone group, 2. group - Levothyroxine group, 3. group - control group٫ 4. group - Levothyron and Prednisolone group. In group 1, the drug taken in patients who only received prednisolone and undergone ovulation induction had no significant effect on Anti-T and Anti-TPO. Biochemically, conceiving rate was 16% higher in this group. In group 2, patients were diagnosed with thyroid disease and were taking levothyroxine for a long time, and they continued to take the drug during ovulation induction. The patients in group 3 (control group) did not take any medication except ovulation induction. Significant decrease was observed in Anti and Anti-TPO values in group 4 (P = 0.037 and P = 0.015, respectively). The combined use of both drugs significantly decreased the biochemical pregnancy rates in this group.