Abstract

Phenolic compounds form one of the main classes of secondary metabolites. The widespread use of flavonoids and phenolic acids necessitates the study of their metabolism. The aim of this work is to predict the possible metabolites of some plant phenolic compounds by a specialized software (OECD (Q)SAR Application Toolbox. Analysis of data reveals that after metabolic activation in liver (observed pathways) for five of the six plant phenolic compounds liver metabolism was not observed. Only for one compound (Luteolin) metabolic activation in liver (observed pathways) was observed.

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