Study of the level of leptin and resistin and some biochemical tests for people using ketogenic diet in Kirkuk city

Abstract

Recently, the keto diet has been relied upon to lose weight, but there are some advantages and disadvantages that could be diagnosed through the current study. The study included 50 individual (male and female) and 25 Control, collected Blood samples for determination of leptin and resistin and Lipid profile. The results showed that the serum level of leptin and resistin were significantly lower in Diet group (2.137 g/l, 4.34 g/l) respectively as compared to healthy control group (leptin; 3.52 g/l, resistin; 4.739g/l) respectively. Lipids profile levels was significantly higher in Ketogenic Diet group, were the results of each (cholestrol -TC, low density lipoprotein-LDL-c, triglycerides -TG) (298 g/dl, 169.9 g/dl, 292.3 g/dl) respectively as compared to healthy control group (159.4 g/dl, 85.4 g/dl, 191 g/dl), while the result of High density lipoprotein (HDL-c) showed lower significantly in Diet group (31.9 g/dl) compared with control group (52.4 g/dl). In conclusion, the results of this study showed following the ketogenic diet increases the level of cholesterol and triglycerides (TG) and causes a reduction in albumin, globulin and total protein levels. The results have also showed an increase in adipokin level and a decrease in leptin level. Whereas, no-significant changes were noticed in both resisten and interlukin-6 levels.