Abstract
The problem of epistaxis has not lost its relevance for many years. The most common cause of epistaxis is hypertension. The purpose of the research was to study the kallikrein-kinin system in the blood of patients with single and recurrent epistaxis due to hypertension. The study of the kallikrein and prekallikrein content was carried out before and after graduated exercise, followed by the calculation of the coefficient of kallikrein formation. Initial activation of the kallikrein-kinin system was revealed in the patients of both groups. In the patients with single epistaxis, further activation of the kallikrein-kinin system after physical activity is observed, while in the patients with recurrent epistaxis, physical activity is not accompanied by a significant increase in its activity.
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