Abstract
This work aimed to evaluate the influence of CaF2 addition in the bioactivity of the samples. The system 60B2O3-4P2O5-18Na2O-xCaF2-(18-xCaO), with x= 0, 5 and 10 wt% was synthetized by melt-quenching method. The in vitro bioactivity of the glasses was investigated by X-ray diffractogram (XRD), Raman, Fourier transform infrared spectroscopy (FTIR) and pH after immersion in SBF solution during 28 days. Results of pH presented an increase after 24 hours of soaking in SBF, which contributes to the dissolution of the external layer of the glass and precipitation of apatite. Hydroxyapatite and fluorapatite formation was confirmed by XRD patterns, Raman and FTIR spectra, confirming the bioactivity of the samples. Cytotoxicity tests were performed on osteoblastic cells. All the samples presented cytotoxicity smaller than 10%, and induced the osteoblast proliferation, indicating a good cytocompatibility and good cell viability. Therefore, the glasses have potential to be applied in biomedical applications, such as odontology and tissue engineering.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
